Table of Contents Executive Summary 1 Industry Overview of Rare Disease Drug 1.1 Definition of Rare Disease Drug 1.2 Rare Disease Drug Segment by Type 1.2.1 Global Rare Disease Drug Production Growth Rate Comparison by Types (2014-2025) 1.2.2 >1‰ 1.2.3 0.65‰～1‰ 1.2.4 <0.1‰ 1.3 Rare Disease Drug Segment by Applications 1.3.1 Global Rare Disease Drug Consumption Comparison by Applications (2014-2025) 1.3.2 Hospital Pharmacies 1.3.3 Speciality Pharmacies 1.3.4 Retail pharmacies 1.3.5 Others 1.4 Global Rare Disease Drug Overall Market 1.4.1 Global Rare Disease Drug Revenue (2014-2025) 1.4.2 Global Rare Disease Drug Production (2014-2025) 1.4.3 North America Rare Disease Drug Status and Prospect (2014-2025) 1.4.4 Europe Rare Disease Drug Status and Prospect (2014-2025) 1.4.5 China Rare Disease Drug Status and Prospect (2014-2025) 1.4.6 Japan Rare Disease Drug Status and Prospect (2014-2025) 1.4.7 Southeast Asia Rare Disease Drug Status and Prospect (2014-2025) 1.4.8 India Rare Disease Drug Status and Prospect (2014-2025) 2 Manufacturing Cost Structure Analysis 2.1 Raw Material and Suppliers 2.2 Manufacturing Cost Structure Analysis of Rare Disease Drug 2.3 Manufacturing Process Analysis of Rare Disease Drug 2.4 Industry Chain Structure of Rare Disease Drug 3 Development and Manufacturing Plants Analysis of Rare Disease Drug 3.1 Capacity and Commercial Production Date 3.2 Global Rare Disease Drug Manufacturing Plants Distribution 3.3 Major Manufacturers Technology Source and Market Position of Rare Disease Drug 3.4 Recent Development and Expansion Plans 4 Key Figures of Major Manufacturers 4.1 Rare Disease Drug Production and Capacity Analysis 4.2 Rare Disease Drug Revenue Analysis 4.3 Rare Disease Drug Price Analysis 4.4 Market Concentration Degree 5 Rare Disease Drug Regional Market Analysis 5.1 Rare Disease Drug Production by Regions 5.1.1 Global Rare Disease Drug Production by Regions 5.1.2 Global Rare Disease Drug Revenue by Regions 5.2 Rare Disease Drug Consumption by Regions 5.3 North America Rare Disease Drug Market Analysis 5.3.1 North America Rare Disease Drug Production 5.3.2 North America Rare Disease Drug Revenue 5.3.3 Key Manufacturers in North America 5.3.4 North America Rare Disease Drug Import and Export 5.4 Europe Rare Disease Drug Market Analysis 5.4.1 Europe Rare Disease Drug Production 5.4.2 Europe Rare Disease Drug Revenue 5.4.3 Key Manufacturers in Europe 5.4.4 Europe Rare Disease Drug Import and Export 5.5 China Rare Disease Drug Market Analysis 5.5.1 China Rare Disease Drug Production 5.5.2 China Rare Disease Drug Revenue 5.5.3 Key Manufacturers in China 5.5.4 China Rare Disease Drug Import and Export 5.6 Japan Rare Disease Drug Market Analysis 5.6.1 Japan Rare Disease Drug Production 5.6.2 Japan Rare Disease Drug Revenue 5.6.3 Key Manufacturers in Japan 5.6.4 Japan Rare Disease Drug Import and Export 5.7 Southeast Asia Rare Disease Drug Market Analysis 5.7.1 Southeast Asia Rare Disease Drug Production 5.7.2 Southeast Asia Rare Disease Drug Revenue 5.7.3 Key Manufacturers in Southeast Asia 5.7.4 Southeast Asia Rare Disease Drug Import and Export 5.8 India Rare Disease Drug Market Analysis 5.8.1 India Rare Disease Drug Production 5.8.2 India Rare Disease Drug Revenue 5.8.3 Key Manufacturers in India 5.8.4 India Rare Disease Drug Import and Export 6 Rare Disease Drug Segment Market Analysis (by Type) 6.1 Global Rare Disease Drug Production by Type 6.2 Global Rare Disease Drug Revenue by Type 6.3 Rare Disease Drug Price by Type 7 Rare Disease Drug Segment Market Analysis (by Application) 7.1 Global Rare Disease Drug Consumption by Application 7.2 Global Rare Disease Drug Consumption Market Share by Application (2014-2019) 8 Rare Disease Drug Major Manufacturers Analysis 8.1 Novartis AG 8.1.1 Novartis AG Rare Disease Drug Production Sites and Area Served 8.1.2 Novartis AG Product Introduction, Application and Specification 8.1.3 Novartis AG Rare Disease Drug Production, Revenue, Ex-factory Price and Gross Margin (2014-2019) 8.1.4 Main Business and Markets Served 8.2 Bristol-Myers Squibb Company 8.2.1 Bristol-Myers Squibb Company Rare Disease Drug Production Sites and Area Served 8.2.2 Bristol-Myers Squibb Company Product Introduction, Application and Specification 8.2.3 Bristol-Myers Squibb Company Rare Disease Drug Production, Revenue, Ex-factory Price and Gross Margin (2014-2019) 8.2.4 Main Business and Markets Served 8.3 Celgene Corporation 8.3.1 Celgene Corporation Rare Disease Drug Production Sites and Area Served 8.3.2 Celgene Corporation Product Introduction, Application and Specification 8.3.3 Celgene Corporation Rare Disease Drug Production, Revenue, Ex-factory Price and Gross Margin (2014-2019) 8.3.4 Main Business and Markets Served 8.4 F. Hoffmann-La Roche Ltd. 8.4.1 F. Hoffmann-La Roche Ltd. Rare Disease Drug Production Sites and Area Served 8.4.2 F. Hoffmann-La Roche Ltd. Product Introduction, Application and Specification 8.4.3 F. Hoffmann-La Roche Ltd. Rare Disease Drug Production, Revenue, Ex-factory Price and Gross Margin (2014-2019) 8.4.4 Main Business and Markets Served 8.5 Pfizer, Inc. 8.5.1 Pfizer, Inc. Rare Disease Drug Production Sites and Area Served 8.5.2 Pfizer, Inc. Product Introduction, Application and Specification 8.5.3 Pfizer, Inc. Rare Disease Drug Production, Revenue, Ex-factory Price and Gross Margin (2014-2019) 8.5.4 Main Business and Markets Served 8.6 Sanofi S.A. 8.6.1 Sanofi S.A. Rare Disease Drug Production Sites and Area Served 8.6.2 Sanofi S.A. Product Introduction, Application and Specification 8.6.3 Sanofi S.A. Rare Disease Drug Production, Revenue, Ex-factory Price and Gross Margin (2014-2019) 8.6.4 Main Business and Markets Served 8.7 Alexion Pharmaceuticals, Inc. 8.7.1 Alexion Pharmaceuticals, Inc. Rare Disease Drug Production Sites and Area Served 8.7.2 Alexion Pharmaceuticals, Inc. Product Introduction, Application and Specification 8.7.3 Alexion Pharmaceuticals, Inc. Rare Disease Drug Production, Revenue, Ex-factory Price and Gross Margin (2014-2019) 8.7.4 Main Business and Markets Served 8.8 Eli Lilly and Company 8.8.1 Eli Lilly and Company Rare Disease Drug Production Sites and Area Served 8.8.2 Eli Lilly and Company Product Introduction, Application and Specification 8.8.3 Eli Lilly and Company Rare Disease Drug Production, Revenue, Ex-factory Price and Gross Margin (2014-2019) 8.8.4 Main Business and Markets Served 8.9 Novo Nordisk A/S 8.9.1 Novo Nordisk A/S Rare Disease Drug Production Sites and Area Served 8.9.2 Novo Nordisk A/S Product Introduction, Application and Specification 8.9.3 Novo Nordisk A/S Rare Disease Drug Production, Revenue, Ex-factory Price and Gross Margin (2014-2019) 8.9.4 Main Business and Markets Served 8.10 AstraZeneca 8.10.1 AstraZeneca Rare Disease Drug Production Sites and Area Served 8.10.2 AstraZeneca Product Introduction, Application and Specification 8.10.3 AstraZeneca Rare Disease Drug Production, Revenue, Ex-factory Price and Gross Margin (2014-2019) 8.10.4 Main Business and Markets Served 8.11 Eisai Co., Ltd. 8.12 Daiichi Sankyo Company Limited 8.13 Bayer AG 8.14 GlaxoSmithKline 8.15 Merck & Co., Inc. 8.16 Johnson & Johnson 8.17 Biogen, Inc. 8.18 Shire 8.19 Amgen, Inc. 8.20 Deciphera 8.21 Atara Biotherapeutics 8.22 ProQR 9 Development Trend of Analysis of Rare Disease Drug Market 9.1 Global Rare Disease Drug Market Trend Analysis 9.1.1 Global Rare Disease Drug Market Size (Volume and Value) Forecast 2019-2025 9.2 Rare Disease Drug Regional Market Trend 9.2.1 North America Rare Disease Drug Forecast 2019-2025 9.2.2 Europe Rare Disease Drug Forecast 2019-2025 9.2.3 China Rare Disease Drug Forecast 2019-2025 9.2.4 Japan Rare Disease Drug Forecast 2019-2025 9.2.5 Southeast Asia Rare Disease Drug Forecast 2019-2025 9.2.6 India Rare Disease Drug Forecast 2019-2025 9.3 Rare Disease Drug Market Trend (Product Type) 9.4 Rare Disease Drug Market Trend (Application) 10.1 Marketing Channel 10.1.1 Direct Marketing 10.1.2 Indirect Marketing 10.3 Rare Disease Drug Customers 11 Market Dynamics 11.1 Market Trends 11.2 Opportunities 11.3 Market Drivers 11.4 Challenges 11.5 Influence Factors 12 Conclusion 13 Appendix 13.1 Methodology/Research Approach 13.1.1 Research Programs/Design 13.1.2 Market Size Estimation 13.1.3 Market Breakdown and Data Triangulation 13.2 Data Source 13.2.1 Secondary Sources 13.2.2 Primary Sources 13.3 Author List 13.4 Disclaimer

List of Tables and Figures Figure Picture of Rare Disease Drug Table Global Rare Disease Drug Production (K Doses) Growth Rate Comparison by Types (2014-2025) Figure Global Rare Disease Drug Production Market Share by Types in 2018 Figure >1‰ Product Picture Figure 0.65‰～1‰ Product Picture Figure <0.1‰ Product Picture Table Global Rare Disease Drug Consumption (K Doses) Comparison by Applications (2014-2025) Figure Global Rare Disease Drug Consumption Market Share by Applications in 2018 Figure Hospital Pharmacies Figure Speciality Pharmacies Figure Retail pharmacies Figure Others Figure Global Rare Disease Drug Revenue (Million USD) (2014-2025) Figure Global Rare Disease Drug Production (K Doses) (2014-2025) Figure North America Rare Disease Drug Market Size (Million USD) (2014-2025) Figure Europe Rare Disease Drug Market Size (Million USD) (2014-2025) Figure China Rare Disease Drug Market Size (Million USD) (2014-2025) Figure Japan Rare Disease Drug Market Size (Million USD) (2014-2025) Figure Southeast Asia Rare Disease Drug Market Size (Million USD) (2014-2025) Figure India Rare Disease Drug Market Size (Million USD) (2014-2025) Table Rare Disease Drug Raw Material and Suppliers Table Manufacturing Cost Structure Analysis of Rare Disease Drug in 2018 Figure Manufacturing Process Analysis of Rare Disease Drug Figure Industry Chain Structure of Rare Disease Drug Table Capacity and Commercial Production Date of Key Manufacturers Table Global Rare Disease Drug Manufacturing Plants Distribution Table Rare Disease Drug Major Manufacturers Technology Source and Market Position Table Recent Development and Expansion Plans in Future Table Rare Disease Drug Capacity (K Doses) of Major Manufacturers (2014-2019) Table Rare Disease Drug Production (K Doses) of Major Manufacturers (2014-2019) Table Rare Disease Drug Production Market Share of Major Manufacturers (2014-2019) Figure Rare Disease Drug Production Share by Manufacturers in 2018 Table Rare Disease Drug Revenue (Million US$) of Major Manufacturers (2014-2019) Table Rare Disease Drug Revenue Market Share of Major Manufacturers (2014-2019) Figure Rare Disease Drug Revenue Share by Manufacturers in 2018 Table Rare Disease Drug Average Price (USD/Dose) of Major Manufacturers (2014-2019) Table Global Manufacturers Market Concentration Ratio (CR5 and HHI) Table Global Rare Disease Drug Production by Regions 2014-2019 (K Doses) Table Global Rare Disease Drug Production Market Share by Regions 2014-2019 Figure Global Rare Disease Drug Production Market Share by Regions in 2018 Table Global Rare Disease Drug Revenue by Regions 2014-2019 (Million USD) Table Global Rare Disease Drug Revenue Market Share by Regions 2014-2019 Figure Global Rare Disease Drug Revenue Market Share by Regions in 2018 Table Global Rare Disease Drug Consumption by Regions 2014-2019 (K Doses) Table Global Rare Disease Drug Consumption Market Share by Regions 2014-2019 Figure North America Rare Disease Drug Production Growth Rate 2014-2019 (K Doses) Figure North America Rare Disease Drug Revenue Growth Rate 2014-2019 (Million USD) Table North America Rare Disease Drug Production, Consumption Import and Export (K Doses) Figure Europe Rare Disease Drug Production Growth Rate 2014-2019 (K Doses) Figure Europe Rare Disease Drug Revenue Growth Rate 2014-2019 (Million USD) Table Europe Rare Disease Drug Production, Consumption Import and Export (K Doses) Figure China Rare Disease Drug Production Growth Rate 2014-2019 (K Doses) Figure China Rare Disease Drug Revenue Growth Rate 2014-2019 (Million USD) Table China Rare Disease Drug Production, Consumption Import and Export (K Doses) Figure Japan Rare Disease Drug Production Growth Rate 2014-2019 (K Doses) Figure Japan Rare Disease Drug Revenue Growth Rate 2014-2019 (Million USD) Table Japan Rare Disease Drug Production, Consumption Import and Export (K Doses) Figure Southeast Asia Rare Disease Drug Production Growth Rate 2014-2019 (K Doses) Figure Southeast Asia Rare Disease Drug Revenue Growth Rate 2014-2019 (Million USD) Table Southeast Asia Rare Disease Drug Production, Consumption Import and Export (K Doses) Figure India Rare Disease Drug Production Growth Rate 2014-2019 (K Doses) Figure India Rare Disease Drug Revenue Growth Rate 2014-2019 (Million USD) Table India Rare Disease Drug Production, Consumption Import and Export (K Doses) Figure Global Consumption Rare Disease Drug Market Share by Application (2014-2019) Figure Global Value (Consumption) Rare Disease Drug Market Share by Application (2014-2019) Table Novartis AG Rare Disease Drug Production Sites and Area Served Table Novartis AG Rare Disease Drug Product Introduction, Application and Specification Table Novartis AG Rare Disease Drug Production (K Doses), Revenue (Million USD), Ex-factory Price (USD/Dose) and Gross Margin (2014-2019) Table Novartis AG Rare Disease Drug Production Growth Rate (2014-2019) Table Novartis AG Rare Disease Drug Production Market Share (2014-2019) Figure Novartis AG Rare Disease Drug Revenue Market Share (2014-2019) Table Novartis AG Rare Disease Drug Main Business and Markets Served Table Bristol-Myers Squibb Company Rare Disease Drug Production Sites and Area Served Table Bristol-Myers Squibb Company Rare Disease Drug Product Introduction, Application and Specification Table Bristol-Myers Squibb Company Rare Disease Drug Production (K Doses), Revenue (Million USD), Ex-factory Price (USD/Dose) and Gross Margin (2014-2019) Table Bristol-Myers Squibb Company Rare Disease Drug Production Growth Rate (2014-2019) Table Bristol-Myers Squibb Company Rare Disease Drug Production Market Share (2014-2019) Figure Bristol-Myers Squibb Company Rare Disease Drug Revenue Market Share (2014-2019) Table Bristol-Myers Squibb Company Rare Disease Drug Main Business and Markets Served Table Celgene Corporation Rare Disease Drug Production Sites and Area Served Table Celgene Corporation Rare Disease Drug Product Introduction, Application and Specification Table Celgene Corporation Rare Disease Drug Production (K Doses), Revenue (Million USD), Ex-factory Price (USD/Dose) and Gross Margin (2014-2019) Table Celgene Corporation Rare Disease Drug Production Growth Rate (2014-2019) Table Celgene Corporation Rare Disease Drug Production Market Share (2014-2019) Figure Celgene Corporation Rare Disease Drug Revenue Market Share (2014-2019) Table Celgene Corporation Rare Disease Drug Main Business and Markets Served Table F. Hoffmann-La Roche Ltd. Rare Disease Drug Production Sites and Area Served Table F. Hoffmann-La Roche Ltd. Rare Disease Drug Product Introduction, Application and Specification Table F. Hoffmann-La Roche Ltd. Rare Disease Drug Production (K Doses), Revenue (Million USD), Ex-factory Price (USD/Dose) and Gross Margin (2014-2019) Table F. Hoffmann-La Roche Ltd. Rare Disease Drug Production Growth Rate (2014-2019) Table F. Hoffmann-La Roche Ltd. Rare Disease Drug Production Market Share (2014-2019) Figure F. Hoffmann-La Roche Ltd. Rare Disease Drug Revenue Market Share (2014-2019) Table F. Hoffmann-La Roche Ltd. Rare Disease Drug Main Business and Markets Served Table Pfizer, Inc. Rare Disease Drug Production Sites and Area Served Table Pfizer, Inc. Rare Disease Drug Product Introduction, Application and Specification Table Pfizer, Inc. Rare Disease Drug Production (K Doses), Revenue (Million USD), Ex-factory Price (USD/Dose) and Gross Margin (2014-2019) Table Pfizer, Inc. Rare Disease Drug Production Growth Rate (2014-2019) Table Pfizer, Inc. Rare Disease Drug Production Market Share (2014-2019) Figure Pfizer, Inc. Rare Disease Drug Revenue Market Share (2014-2019) Table Pfizer, Inc. Rare Disease Drug Main Business and Markets Served Table Sanofi S.A. Rare Disease Drug Production Sites and Area Served Table Sanofi S.A. Rare Disease Drug Product Introduction, Application and Specification Table Sanofi S.A. Rare Disease Drug Production (K Doses), Revenue (Million USD), Ex-factory Price (USD/Dose) and Gross Margin (2014-2019) Table Sanofi S.A. Rare Disease Drug Production Growth Rate (2014-2019) Table Sanofi S.A. Rare Disease Drug Production Market Share (2014-2019) Figure Sanofi S.A. Rare Disease Drug Revenue Market Share (2014-2019) Table Sanofi S.A. Rare Disease Drug Main Business and Markets Served Table Alexion Pharmaceuticals, Inc. Rare Disease Drug Production Sites and Area Served Table Alexion Pharmaceuticals, Inc. Rare Disease Drug Product Introduction, Application and Specification Table Alexion Pharmaceuticals, Inc. Rare Disease Drug Production (K Doses), Revenue (Million USD), Ex-factory Price (USD/Dose) and Gross Margin (2014-2019) Table Alexion Pharmaceuticals, Inc. Rare Disease Drug Production Growth Rate (2014-2019) Table Alexion Pharmaceuticals, Inc. Rare Disease Drug Production Market Share (2014-2019) Figure Alexion Pharmaceuticals, Inc. Rare Disease Drug Revenue Market Share (2014-2019) Table Alexion Pharmaceuticals, Inc. Rare Disease Drug Main Business and Markets Served Table Eli Lilly and Company Rare Disease Drug Production Sites and Area Served Table Eli Lilly and Company Rare Disease Drug Product Introduction, Application and Specification Table Eli Lilly and Company Rare Disease Drug Production (K Doses), Revenue (Million USD), Ex-factory Price (USD/Dose) and Gross Margin (2014-2019) Table Eli Lilly and Company Rare Disease Drug Production Growth Rate (2014-2019) Table Eli Lilly and Company Rare Disease Drug Production Market Share (2014-2019) Figure Eli Lilly and Company Rare Disease Drug Revenue Market Share (2014-2019) Table Eli Lilly and Company Rare Disease Drug Main Business and Markets Served Table Novo Nordisk A/S Rare Disease Drug Production Sites and Area Served Table Novo Nordisk A/S Rare Disease Drug Product Introduction, Application and Specification Table Novo Nordisk A/S Rare Disease Drug Production (K Doses), Revenue (Million USD), Ex-factory Price (USD/Dose) and Gross Margin (2014-2019) Table Novo Nordisk A/S Rare Disease Drug Production Growth Rate (2014-2019) Table Novo Nordisk A/S Rare Disease Drug Production Market Share (2014-2019) Figure Novo Nordisk A/S Rare Disease Drug Revenue Market Share (2014-2019) Table Novo Nordisk A/S Rare Disease Drug Main Business and Markets Served Table AstraZeneca Rare Disease Drug Production Sites and Area Served Table AstraZeneca Rare Disease Drug Product Introduction, Application and Specification Table AstraZeneca Rare Disease Drug Production (K Doses), Revenue (Million USD), Ex-factory Price (USD/Dose) and Gross Margin (2014-2019) Table AstraZeneca Rare Disease Drug Production Growth Rate (2014-2019) Table AstraZeneca Rare Disease Drug Production Market Share (2014-2019) Figure AstraZeneca Rare Disease Drug Revenue Market Share (2014-2019) Table AstraZeneca Rare Disease Drug Main Business and Markets Served Table Eisai Co., Ltd. Rare Disease Drug Production Sites and Area Served Table Daiichi Sankyo Company Limited Rare Disease Drug Production Sites and Area Served Table Bayer AG Rare Disease Drug Production Sites and Area Served Table GlaxoSmithKline Rare Disease Drug Production Sites and Area Served Table Merck & Co., Inc. Rare Disease Drug Production Sites and Area Served Table Johnson & Johnson Rare Disease Drug Production Sites and Area Served Table Biogen, Inc. Rare Disease Drug Production Sites and Area Served Table Shire Rare Disease Drug Production Sites and Area Served Table Amgen, Inc. Rare Disease Drug Production Sites and Area Served Table Deciphera Rare Disease Drug Production Sites and Area Served Table Atara Biotherapeutics Rare Disease Drug Production Sites and Area Served Table ProQR Rare Disease Drug Production Sites and Area Served Figure Global Rare Disease Drug Production (K Doses) Growth Rate Forecast 2019-2025 Figure Global Rare Disease Drug Revenue (Million USD) Growth Rate Forecast 2019-2025 Figure Global Rare Disease Drug Sales Price (USD/Dose) Forecast 2019-2025 Figure North America Rare Disease Drug Production Growth Rate Forecast 2019-2025 (K Doses) Figure North America Rare Disease Drug Revenue Growth Rate Forecast 2019-2025 (Million USD) Figure Europe Rare Disease Drug Production Growth Rate Forecast 2019-2025 (K Doses) Figure Europe Rare Disease Drug Revenue Growth Rate Forecast 2019-2025 (Million USD) Figure China Rare Disease Drug Production Growth Rate Forecast 2019-2025 (K Doses) Figure China Rare Disease Drug Revenue Growth Rate Forecast 2019-2025 (Million USD) Figure Japan Rare Disease Drug Production Growth Rate Forecast 2019-2025 (K Doses) Figure Japan Rare Disease Drug Revenue Growth Rate Forecast 2019-2025 (Million USD) Figure Southeast Asia Rare Disease Drug Production Growth Rate Forecast 2019-2025 (K Doses) Figure Southeast Asia Rare Disease Drug Revenue Growth Rate Forecast 2019-2025 (Million USD) Figure India Rare Disease Drug Production Growth Rate Forecast 2019-2025 (K Doses) Figure India Rare Disease Drug Revenue Growth Rate Forecast 2019-2025 (Million USD) Table Global Production (K Doses) of Rare Disease Drug by Type (2019-2025) Table Global Consumption (K Doses) of Rare Disease Drug by Application (2019-2025) Table Rare Disease Drug Distributors List Table Rare Disease Drug Customers List Table Market Key Trends Table Key Opportunities Table Market Key Drivers Table Key Challenges Table Key Influence Factors Table Research Programs/Design for This Report Figure Bottom-up and Top-down Approaches for This Report Figure Data Triangulation Table Key Data Information from Secondary Sources Table Key Data Information from Primary Sources

Novartis AG Bristol-Myers Squibb Company Celgene Corporation F. Hoffmann-La Roche Ltd. Pfizer, Inc. Sanofi S.A. Alexion Pharmaceuticals, Inc. Eli Lilly and Company Novo Nordisk A/S AstraZeneca Eisai Co., Ltd. Daiichi Sankyo Company Limited Bayer AG GlaxoSmithKline Merck & Co., Inc. Johnson & Johnson Biogen, Inc. Shire Amgen, Inc. Deciphera Atara Biotherapeutics ProQR