Table of Contents Executive Summary 1 Industry Overview of Acid Sphingomyelinase Deficiency Drug 1.1 Definition of Acid Sphingomyelinase Deficiency Drug 1.2 Acid Sphingomyelinase Deficiency Drug Segment by Type 1.2.1 Global Acid Sphingomyelinase Deficiency Drug Production Growth Rate Comparison by Types (2014-2025) 1.2.2 LJPC-0712 1.2.3 ML-SA1 1.2.4 OKL-1014 1.2.5 Olipudase Alfa 1.2.6 OR-0005 1.2.7 Others 1.3 Acid Sphingomyelinase Deficiency Drug Segment by Applications 1.3.1 Global Acid Sphingomyelinase Deficiency Drug Consumption Comparison by Applications (2014-2025) 1.3.2 Hospital 1.3.3 Clinic 1.3.4 Others 1.4 Global Acid Sphingomyelinase Deficiency Drug Overall Market 1.4.1 Global Acid Sphingomyelinase Deficiency Drug Revenue (2014-2025) 1.4.2 Global Acid Sphingomyelinase Deficiency Drug Production (2014-2025) 1.4.3 North America Acid Sphingomyelinase Deficiency Drug Status and Prospect (2014-2025) 1.4.4 Europe Acid Sphingomyelinase Deficiency Drug Status and Prospect (2014-2025) 1.4.5 China Acid Sphingomyelinase Deficiency Drug Status and Prospect (2014-2025) 1.4.6 Japan Acid Sphingomyelinase Deficiency Drug Status and Prospect (2014-2025) 1.4.7 Southeast Asia Acid Sphingomyelinase Deficiency Drug Status and Prospect (2014-2025) 1.4.8 India Acid Sphingomyelinase Deficiency Drug Status and Prospect (2014-2025) 2 Manufacturing Cost Structure Analysis 2.1 Raw Material and Suppliers 2.2 Manufacturing Cost Structure Analysis of Acid Sphingomyelinase Deficiency Drug 2.3 Manufacturing Process Analysis of Acid Sphingomyelinase Deficiency Drug 2.4 Industry Chain Structure of Acid Sphingomyelinase Deficiency Drug 3 Development and Manufacturing Plants Analysis of Acid Sphingomyelinase Deficiency Drug 3.1 Capacity and Commercial Production Date 3.2 Global Acid Sphingomyelinase Deficiency Drug Manufacturing Plants Distribution 3.3 Major Manufacturers Technology Source and Market Position of Acid Sphingomyelinase Deficiency Drug 3.4 Recent Development and Expansion Plans 4 Key Figures of Major Manufacturers 4.1 Acid Sphingomyelinase Deficiency Drug Production and Capacity Analysis 4.2 Acid Sphingomyelinase Deficiency Drug Revenue Analysis 4.3 Acid Sphingomyelinase Deficiency Drug Price Analysis 4.4 Market Concentration Degree 5 Acid Sphingomyelinase Deficiency Drug Regional Market Analysis 5.1 Acid Sphingomyelinase Deficiency Drug Production by Regions 5.1.1 Global Acid Sphingomyelinase Deficiency Drug Production by Regions 5.1.2 Global Acid Sphingomyelinase Deficiency Drug Revenue by Regions 5.2 Acid Sphingomyelinase Deficiency Drug Consumption by Regions 5.3 North America Acid Sphingomyelinase Deficiency Drug Market Analysis 5.3.1 North America Acid Sphingomyelinase Deficiency Drug Production 5.3.2 North America Acid Sphingomyelinase Deficiency Drug Revenue 5.3.3 Key Manufacturers in North America 5.3.4 North America Acid Sphingomyelinase Deficiency Drug Import and Export 5.4 Europe Acid Sphingomyelinase Deficiency Drug Market Analysis 5.4.1 Europe Acid Sphingomyelinase Deficiency Drug Production 5.4.2 Europe Acid Sphingomyelinase Deficiency Drug Revenue 5.4.3 Key Manufacturers in Europe 5.4.4 Europe Acid Sphingomyelinase Deficiency Drug Import and Export 5.5 China Acid Sphingomyelinase Deficiency Drug Market Analysis 5.5.1 China Acid Sphingomyelinase Deficiency Drug Production 5.5.2 China Acid Sphingomyelinase Deficiency Drug Revenue 5.5.3 Key Manufacturers in China 5.5.4 China Acid Sphingomyelinase Deficiency Drug Import and Export 5.6 Japan Acid Sphingomyelinase Deficiency Drug Market Analysis 5.6.1 Japan Acid Sphingomyelinase Deficiency Drug Production 5.6.2 Japan Acid Sphingomyelinase Deficiency Drug Revenue 5.6.3 Key Manufacturers in Japan 5.6.4 Japan Acid Sphingomyelinase Deficiency Drug Import and Export 5.7 Southeast Asia Acid Sphingomyelinase Deficiency Drug Market Analysis 5.7.1 Southeast Asia Acid Sphingomyelinase Deficiency Drug Production 5.7.2 Southeast Asia Acid Sphingomyelinase Deficiency Drug Revenue 5.7.3 Key Manufacturers in Southeast Asia 5.7.4 Southeast Asia Acid Sphingomyelinase Deficiency Drug Import and Export 5.8 India Acid Sphingomyelinase Deficiency Drug Market Analysis 5.8.1 India Acid Sphingomyelinase Deficiency Drug Production 5.8.2 India Acid Sphingomyelinase Deficiency Drug Revenue 5.8.3 Key Manufacturers in India 5.8.4 India Acid Sphingomyelinase Deficiency Drug Import and Export 6 Acid Sphingomyelinase Deficiency Drug Segment Market Analysis (by Type) 6.1 Global Acid Sphingomyelinase Deficiency Drug Production by Type 6.2 Global Acid Sphingomyelinase Deficiency Drug Revenue by Type 6.3 Acid Sphingomyelinase Deficiency Drug Price by Type 7 Acid Sphingomyelinase Deficiency Drug Segment Market Analysis (by Application) 7.1 Global Acid Sphingomyelinase Deficiency Drug Consumption by Application 7.2 Global Acid Sphingomyelinase Deficiency Drug Consumption Market Share by Application (2014-2019) 8 Acid Sphingomyelinase Deficiency Drug Major Manufacturers Analysis 8.1 Genzyme Corporation 8.1.1 Genzyme Corporation Acid Sphingomyelinase Deficiency Drug Production Sites and Area Served 8.1.2 Genzyme Corporation Product Introduction, Application and Specification 8.1.3 Genzyme Corporation Acid Sphingomyelinase Deficiency Drug Production, Revenue, Ex-factory Price and Gross Margin (2014-2019) 8.1.4 Main Business and Markets Served 8.2 La Jolla Pharmaceutical Company 8.2.1 La Jolla Pharmaceutical Company Acid Sphingomyelinase Deficiency Drug Production Sites and Area Served 8.2.2 La Jolla Pharmaceutical Company Product Introduction, Application and Specification 8.2.3 La Jolla Pharmaceutical Company Acid Sphingomyelinase Deficiency Drug Production, Revenue, Ex-factory Price and Gross Margin (2014-2019) 8.2.4 Main Business and Markets Served 8.3 Merck & Co., Inc. 8.3.1 Merck & Co., Inc. Acid Sphingomyelinase Deficiency Drug Production Sites and Area Served 8.3.2 Merck & Co., Inc. Product Introduction, Application and Specification 8.3.3 Merck & Co., Inc. Acid Sphingomyelinase Deficiency Drug Production, Revenue, Ex-factory Price and Gross Margin (2014-2019) 8.3.4 Main Business and Markets Served 8.4 Okklo Life Sciences BV 8.4.1 Okklo Life Sciences BV Acid Sphingomyelinase Deficiency Drug Production Sites and Area Served 8.4.2 Okklo Life Sciences BV Product Introduction, Application and Specification 8.4.3 Okklo Life Sciences BV Acid Sphingomyelinase Deficiency Drug Production, Revenue, Ex-factory Price and Gross Margin (2014-2019) 8.4.4 Main Business and Markets Served 8.5 Orphazyme ApS 8.5.1 Orphazyme ApS Acid Sphingomyelinase Deficiency Drug Production Sites and Area Served 8.5.2 Orphazyme ApS Product Introduction, Application and Specification 8.5.3 Orphazyme ApS Acid Sphingomyelinase Deficiency Drug Production, Revenue, Ex-factory Price and Gross Margin (2014-2019) 8.5.4 Main Business and Markets Served 9 Development Trend of Analysis of Acid Sphingomyelinase Deficiency Drug Market 9.1 Global Acid Sphingomyelinase Deficiency Drug Market Trend Analysis 9.1.1 Global Acid Sphingomyelinase Deficiency Drug Market Size (Volume and Value) Forecast 2019-2025 9.2 Acid Sphingomyelinase Deficiency Drug Regional Market Trend 9.2.1 North America Acid Sphingomyelinase Deficiency Drug Forecast 2019-2025 9.2.2 Europe Acid Sphingomyelinase Deficiency Drug Forecast 2019-2025 9.2.3 China Acid Sphingomyelinase Deficiency Drug Forecast 2019-2025 9.2.4 Japan Acid Sphingomyelinase Deficiency Drug Forecast 2019-2025 9.2.5 Southeast Asia Acid Sphingomyelinase Deficiency Drug Forecast 2019-2025 9.2.6 India Acid Sphingomyelinase Deficiency Drug Forecast 2019-2025 9.3 Acid Sphingomyelinase Deficiency Drug Market Trend (Product Type) 9.4 Acid Sphingomyelinase Deficiency Drug Market Trend (Application) 10.1 Marketing Channel 10.1.1 Direct Marketing 10.1.2 Indirect Marketing 10.3 Acid Sphingomyelinase Deficiency Drug Customers 11 Market Dynamics 11.1 Market Trends 11.2 Opportunities 11.3 Market Drivers 11.4 Challenges 11.5 Influence Factors 12 Conclusion 13 Appendix 13.1 Methodology/Research Approach 13.1.1 Research Programs/Design 13.1.2 Market Size Estimation 13.1.3 Market Breakdown and Data Triangulation 13.2 Data Source 13.2.1 Secondary Sources 13.2.2 Primary Sources 13.3 Author List 13.4 Disclaimer

List of Tables and Figures Figure Picture of Acid Sphingomyelinase Deficiency Drug Table Global Acid Sphingomyelinase Deficiency Drug Production (K Pcs) Growth Rate Comparison by Types (2014-2025) Figure Global Acid Sphingomyelinase Deficiency Drug Production Market Share by Types in 2018 Figure LJPC-0712 Product Picture Figure ML-SA1 Product Picture Figure OKL-1014 Product Picture Figure Olipudase Alfa Product Picture Figure OR-0005 Product Picture Figure Others Product Picture Table Global Acid Sphingomyelinase Deficiency Drug Consumption (K Pcs) Comparison by Applications (2014-2025) Figure Global Acid Sphingomyelinase Deficiency Drug Consumption Market Share by Applications in 2018 Figure Hospital Figure Clinic Figure Others Figure Global Acid Sphingomyelinase Deficiency Drug Revenue (Million USD) (2014-2025) Figure Global Acid Sphingomyelinase Deficiency Drug Production (K Pcs) (2014-2025) Figure North America Acid Sphingomyelinase Deficiency Drug Market Size (Million USD) (2014-2025) Figure Europe Acid Sphingomyelinase Deficiency Drug Market Size (Million USD) (2014-2025) Figure China Acid Sphingomyelinase Deficiency Drug Market Size (Million USD) (2014-2025) Figure Japan Acid Sphingomyelinase Deficiency Drug Market Size (Million USD) (2014-2025) Figure Southeast Asia Acid Sphingomyelinase Deficiency Drug Market Size (Million USD) (2014-2025) Figure India Acid Sphingomyelinase Deficiency Drug Market Size (Million USD) (2014-2025) Table Acid Sphingomyelinase Deficiency Drug Raw Material and Suppliers Table Manufacturing Cost Structure Analysis of Acid Sphingomyelinase Deficiency Drug in 2018 Figure Manufacturing Process Analysis of Acid Sphingomyelinase Deficiency Drug Figure Industry Chain Structure of Acid Sphingomyelinase Deficiency Drug Table Capacity and Commercial Production Date of Key Manufacturers Table Global Acid Sphingomyelinase Deficiency Drug Manufacturing Plants Distribution Table Acid Sphingomyelinase Deficiency Drug Major Manufacturers Technology Source and Market Position Table Recent Development and Expansion Plans in Future Table Acid Sphingomyelinase Deficiency Drug Capacity (K Pcs) of Major Manufacturers (2014-2019) Table Acid Sphingomyelinase Deficiency Drug Production (K Pcs) of Major Manufacturers (2014-2019) Table Acid Sphingomyelinase Deficiency Drug Production Market Share of Major Manufacturers (2014-2019) Figure Acid Sphingomyelinase Deficiency Drug Production Share by Manufacturers in 2018 Table Acid Sphingomyelinase Deficiency Drug Revenue (Million US$) of Major Manufacturers (2014-2019) Table Acid Sphingomyelinase Deficiency Drug Revenue Market Share of Major Manufacturers (2014-2019) Figure Acid Sphingomyelinase Deficiency Drug Revenue Share by Manufacturers in 2018 Table Acid Sphingomyelinase Deficiency Drug Average Price (USD/Pcs) of Major Manufacturers (2014-2019) Table Global Manufacturers Market Concentration Ratio (CR5 and HHI) Table Global Acid Sphingomyelinase Deficiency Drug Production by Regions 2014-2019 (K Pcs) Table Global Acid Sphingomyelinase Deficiency Drug Production Market Share by Regions 2014-2019 Figure Global Acid Sphingomyelinase Deficiency Drug Production Market Share by Regions in 2018 Table Global Acid Sphingomyelinase Deficiency Drug Revenue by Regions 2014-2019 (Million USD) Table Global Acid Sphingomyelinase Deficiency Drug Revenue Market Share by Regions 2014-2019 Figure Global Acid Sphingomyelinase Deficiency Drug Revenue Market Share by Regions in 2018 Table Global Acid Sphingomyelinase Deficiency Drug Consumption by Regions 2014-2019 (K Pcs) Table Global Acid Sphingomyelinase Deficiency Drug Consumption Market Share by Regions 2014-2019 Figure North America Acid Sphingomyelinase Deficiency Drug Production Growth Rate 2014-2019 (K Pcs) Figure North America Acid Sphingomyelinase Deficiency Drug Revenue Growth Rate 2014-2019 (Million USD) Table North America Acid Sphingomyelinase Deficiency Drug Production, Consumption Import and Export (K Pcs) Figure Europe Acid Sphingomyelinase Deficiency Drug Production Growth Rate 2014-2019 (K Pcs) Figure Europe Acid Sphingomyelinase Deficiency Drug Revenue Growth Rate 2014-2019 (Million USD) Table Europe Acid Sphingomyelinase Deficiency Drug Production, Consumption Import and Export (K Pcs) Figure China Acid Sphingomyelinase Deficiency Drug Production Growth Rate 2014-2019 (K Pcs) Figure China Acid Sphingomyelinase Deficiency Drug Revenue Growth Rate 2014-2019 (Million USD) Table China Acid Sphingomyelinase Deficiency Drug Production, Consumption Import and Export (K Pcs) Figure Japan Acid Sphingomyelinase Deficiency Drug Production Growth Rate 2014-2019 (K Pcs) Figure Japan Acid Sphingomyelinase Deficiency Drug Revenue Growth Rate 2014-2019 (Million USD) Table Japan Acid Sphingomyelinase Deficiency Drug Production, Consumption Import and Export (K Pcs) Figure Southeast Asia Acid Sphingomyelinase Deficiency Drug Production Growth Rate 2014-2019 (K Pcs) Figure Southeast Asia Acid Sphingomyelinase Deficiency Drug Revenue Growth Rate 2014-2019 (Million USD) Table Southeast Asia Acid Sphingomyelinase Deficiency Drug Production, Consumption Import and Export (K Pcs) Figure India Acid Sphingomyelinase Deficiency Drug Production Growth Rate 2014-2019 (K Pcs) Figure India Acid Sphingomyelinase Deficiency Drug Revenue Growth Rate 2014-2019 (Million USD) Table India Acid Sphingomyelinase Deficiency Drug Production, Consumption Import and Export (K Pcs) Figure Global Consumption Acid Sphingomyelinase Deficiency Drug Market Share by Application (2014-2019) Figure Global Value (Consumption) Acid Sphingomyelinase Deficiency Drug Market Share by Application (2014-2019) Table Genzyme Corporation Acid Sphingomyelinase Deficiency Drug Production Sites and Area Served Table Genzyme Corporation Acid Sphingomyelinase Deficiency Drug Product Introduction, Application and Specification Table Genzyme Corporation Acid Sphingomyelinase Deficiency Drug Production (K Pcs), Revenue (Million USD), Ex-factory Price (USD/Pcs) and Gross Margin (2014-2019) Table Genzyme Corporation Acid Sphingomyelinase Deficiency Drug Production Growth Rate (2014-2019) Table Genzyme Corporation Acid Sphingomyelinase Deficiency Drug Production Market Share (2014-2019) Figure Genzyme Corporation Acid Sphingomyelinase Deficiency Drug Revenue Market Share (2014-2019) Table Genzyme Corporation Acid Sphingomyelinase Deficiency Drug Main Business and Markets Served Table La Jolla Pharmaceutical Company Acid Sphingomyelinase Deficiency Drug Production Sites and Area Served Table La Jolla Pharmaceutical Company Acid Sphingomyelinase Deficiency Drug Product Introduction, Application and Specification Table La Jolla Pharmaceutical Company Acid Sphingomyelinase Deficiency Drug Production (K Pcs), Revenue (Million USD), Ex-factory Price (USD/Pcs) and Gross Margin (2014-2019) Table La Jolla Pharmaceutical Company Acid Sphingomyelinase Deficiency Drug Production Growth Rate (2014-2019) Table La Jolla Pharmaceutical Company Acid Sphingomyelinase Deficiency Drug Production Market Share (2014-2019) Figure La Jolla Pharmaceutical Company Acid Sphingomyelinase Deficiency Drug Revenue Market Share (2014-2019) Table La Jolla Pharmaceutical Company Acid Sphingomyelinase Deficiency Drug Main Business and Markets Served Table Merck & Co., Inc. Acid Sphingomyelinase Deficiency Drug Production Sites and Area Served Table Merck & Co., Inc. Acid Sphingomyelinase Deficiency Drug Product Introduction, Application and Specification Table Merck & Co., Inc. Acid Sphingomyelinase Deficiency Drug Production (K Pcs), Revenue (Million USD), Ex-factory Price (USD/Pcs) and Gross Margin (2014-2019) Table Merck & Co., Inc. Acid Sphingomyelinase Deficiency Drug Production Growth Rate (2014-2019) Table Merck & Co., Inc. Acid Sphingomyelinase Deficiency Drug Production Market Share (2014-2019) Figure Merck & Co., Inc. Acid Sphingomyelinase Deficiency Drug Revenue Market Share (2014-2019) Table Merck & Co., Inc. Acid Sphingomyelinase Deficiency Drug Main Business and Markets Served Table Okklo Life Sciences BV Acid Sphingomyelinase Deficiency Drug Production Sites and Area Served Table Okklo Life Sciences BV Acid Sphingomyelinase Deficiency Drug Product Introduction, Application and Specification Table Okklo Life Sciences BV Acid Sphingomyelinase Deficiency Drug Production (K Pcs), Revenue (Million USD), Ex-factory Price (USD/Pcs) and Gross Margin (2014-2019) Table Okklo Life Sciences BV Acid Sphingomyelinase Deficiency Drug Production Growth Rate (2014-2019) Table Okklo Life Sciences BV Acid Sphingomyelinase Deficiency Drug Production Market Share (2014-2019) Figure Okklo Life Sciences BV Acid Sphingomyelinase Deficiency Drug Revenue Market Share (2014-2019) Table Okklo Life Sciences BV Acid Sphingomyelinase Deficiency Drug Main Business and Markets Served Table Orphazyme ApS Acid Sphingomyelinase Deficiency Drug Production Sites and Area Served Table Orphazyme ApS Acid Sphingomyelinase Deficiency Drug Product Introduction, Application and Specification Table Orphazyme ApS Acid Sphingomyelinase Deficiency Drug Production (K Pcs), Revenue (Million USD), Ex-factory Price (USD/Pcs) and Gross Margin (2014-2019) Table Orphazyme ApS Acid Sphingomyelinase Deficiency Drug Production Growth Rate (2014-2019) Table Orphazyme ApS Acid Sphingomyelinase Deficiency Drug Production Market Share (2014-2019) Figure Orphazyme ApS Acid Sphingomyelinase Deficiency Drug Revenue Market Share (2014-2019) Table Orphazyme ApS Acid Sphingomyelinase Deficiency Drug Main Business and Markets Served Figure Global Acid Sphingomyelinase Deficiency Drug Production (K Pcs) Growth Rate Forecast 2019-2025 Figure Global Acid Sphingomyelinase Deficiency Drug Revenue (Million USD) Growth Rate Forecast 2019-2025 Figure Global Acid Sphingomyelinase Deficiency Drug Sales Price (USD/Pcs) Forecast 2019-2025 Figure North America Acid Sphingomyelinase Deficiency Drug Production Growth Rate Forecast 2019-2025 (K Pcs) Figure North America Acid Sphingomyelinase Deficiency Drug Revenue Growth Rate Forecast 2019-2025 (Million USD) Figure Europe Acid Sphingomyelinase Deficiency Drug Production Growth Rate Forecast 2019-2025 (K Pcs) Figure Europe Acid Sphingomyelinase Deficiency Drug Revenue Growth Rate Forecast 2019-2025 (Million USD) Figure China Acid Sphingomyelinase Deficiency Drug Production Growth Rate Forecast 2019-2025 (K Pcs) Figure China Acid Sphingomyelinase Deficiency Drug Revenue Growth Rate Forecast 2019-2025 (Million USD) Figure Japan Acid Sphingomyelinase Deficiency Drug Production Growth Rate Forecast 2019-2025 (K Pcs) Figure Japan Acid Sphingomyelinase Deficiency Drug Revenue Growth Rate Forecast 2019-2025 (Million USD) Figure Southeast Asia Acid Sphingomyelinase Deficiency Drug Production Growth Rate Forecast 2019-2025 (K Pcs) Figure Southeast Asia Acid Sphingomyelinase Deficiency Drug Revenue Growth Rate Forecast 2019-2025 (Million USD) Figure India Acid Sphingomyelinase Deficiency Drug Production Growth Rate Forecast 2019-2025 (K Pcs) Figure India Acid Sphingomyelinase Deficiency Drug Revenue Growth Rate Forecast 2019-2025 (Million USD) Table Global Production (K Pcs) of Acid Sphingomyelinase Deficiency Drug by Type (2019-2025) Table Global Consumption (K Pcs) of Acid Sphingomyelinase Deficiency Drug by Application (2019-2025) Table Acid Sphingomyelinase Deficiency Drug Distributors List Table Acid Sphingomyelinase Deficiency Drug Customers List Table Market Key Trends Table Key Opportunities Table Market Key Drivers Table Key Challenges Table Key Influence Factors Table Research Programs/Design for This Report Figure Bottom-up and Top-down Approaches for This Report Figure Data Triangulation Table Key Data Information from Secondary Sources Table Key Data Information from Primary Sources

Genzyme Corporation La Jolla Pharmaceutical Company Merck & Co., Inc. Okklo Life Sciences BV Orphazyme ApS