Table of Contents 1 Market Overview 1.1 Heart Blocks Treatment Devices Introduction 1.2 Market Analysis by Type 1.2.1 Sinoatrial node (SA node) nodal block 1.2.2 Atrioventricular node (AV node) nodal block 1.3 Market Analysis by Applications 1.3.1 Hosptial 1.3.2 Clinic 1.4 Market Analysis by Regions 1.4.1 North America (United States, Canada and Mexico) 1.4.1.1 United States Market States and Outlook (2013-2023) 1.4.1.2 Canada Market States and Outlook (2013-2023) 1.4.1.3 Mexico Market States and Outlook (2013-2023) 1.4.2 Europe (Germany, France, UK, Russia and Italy) 1.4.2.1 Germany Market States and Outlook (2013-2023) 1.4.2.2 France Market States and Outlook (2013-2023) 1.4.2.3 UK Market States and Outlook (2013-2023) 1.4.2.4 Russia Market States and Outlook (2013-2023) 1.4.2.5 Italy Market States and Outlook (2013-2023) 1.4.3 Asia-Pacific (China, Japan, Korea, India and Southeast Asia) 1.4.3.1 China Market States and Outlook (2013-2023) 1.4.3.2 Japan Market States and Outlook (2013-2023) 1.4.3.3 Korea Market States and Outlook (2013-2023) 1.4.3.4 India Market States and Outlook (2013-2023) 1.4.3.5 Southeast Asia Market States and Outlook (2013-2023) 1.4.4 South America, Middle East and Africa 1.4.4.1 Brazil Market States and Outlook (2013-2023) 1.4.4.2 Egypt Market States and Outlook (2013-2023) 1.4.4.3 Saudi Arabia Market States and Outlook (2013-2023) 1.4.4.4 South Africa Market States and Outlook (2013-2023) 1.4.4.5 Nigeria Market States and Outlook (2013-2023) 1.5 Market Dynamics 1.5.1 Market Opportunities 1.5.2 Market Risk 1.5.3 Market Driving Force 2 Manufacturers Profiles 2.1 Medtronic, Inc. 2.1.1 Business Overview 2.1.2 Heart Blocks Treatment Devices Type and Applications 2.1.2.1 Product A 2.1.2.2 Product B 2.1.3 Medtronic, Inc. Heart Blocks Treatment Devices Sales, Price, Revenue, Gross Margin and Market Share (2016-2017) 2.2 Boston Scientific Corporation 2.2.1 Business Overview 2.2.2 Heart Blocks Treatment Devices Type and Applications 2.2.2.1 Product A 2.2.2.2 Product B 2.2.3 Boston Scientific Corporation Heart Blocks Treatment Devices Sales, Price, Revenue, Gross Margin and Market Share (2016-2017) 2.3 St. Jude Medical, Inc. 2.3.1 Business Overview 2.3.2 Heart Blocks Treatment Devices Type and Applications 2.3.2.1 Product A 2.3.2.2 Product B 2.3.3 St. Jude Medical, Inc. Heart Blocks Treatment Devices Sales, Price, Revenue, Gross Margin and Market Share (2016-2017) 2.4 BIOTRONIK SE & Co. KG 2.4.1 Business Overview 2.4.2 Heart Blocks Treatment Devices Type and Applications 2.4.2.1 Product A 2.4.2.2 Product B 2.4.3 BIOTRONIK SE & Co. KG Heart Blocks Treatment Devices Sales, Price, Revenue, Gross Margin and Market Share (2016-2017) 2.5 SORIN S.p.A. 2.5.1 Business Overview 2.5.2 Heart Blocks Treatment Devices Type and Applications 2.5.2.1 Product A 2.5.2.2 Product B 2.5.3 SORIN S.p.A. Heart Blocks Treatment Devices Sales, Price, Revenue, Gross Margin and Market Share (2016-2017) 3 Global Heart Blocks Treatment Devices Sales, Revenue, Market Share and Competition by Manufacturer (2016-2017) 3.1 Global Heart Blocks Treatment Devices Sales and Market Share by Manufacturer (2016-2017) 3.2 Global Heart Blocks Treatment Devices Revenue and Market Share by Manufacturer (2016-2017) 3.3 Market Concentration Rate 3.3.1 Top 3 Heart Blocks Treatment Devices Manufacturer Market Share in 2017 3.3.2 Top 6 Heart Blocks Treatment Devices Manufacturer Market Share in 2017 3.4 Market Competition Trend 4 Global Heart Blocks Treatment Devices Market Analysis by Regions 4.1 Global Heart Blocks Treatment Devices Sales, Revenue and Market Share by Regions 4.1.1 Global Heart Blocks Treatment Devices Sales and Market Share by Regions (2013-2018) 4.1.2 Global Heart Blocks Treatment Devices Revenue and Market Share by Regions (2013-2018) 4.2 North America Heart Blocks Treatment Devices Sales and Growth Rate (2013-2018) 4.3 Europe Heart Blocks Treatment Devices Sales and Growth Rate (2013-2018) 4.4 Asia-Pacific Heart Blocks Treatment Devices Sales and Growth Rate (2013-2018) 4.5 South America Heart Blocks Treatment Devices Sales and Growth Rate (2013-2018) 4.6 Middle East and Africa Heart Blocks Treatment Devices Sales and Growth Rate (2013-2018) 5 North America Heart Blocks Treatment Devices by Countries 5.1 North America Heart Blocks Treatment Devices Sales, Revenue and Market Share by Countries 5.1.1 North America Heart Blocks Treatment Devices Sales and Market Share by Countries (2013-2018) 5.1.2 North America Heart Blocks Treatment Devices Revenue and Market Share by Countries (2013-2018) 5.2 United States Heart Blocks Treatment Devices Sales and Growth Rate (2013-2018) 5.3 Canada Heart Blocks Treatment Devices Sales and Growth Rate (2013-2018) 5.4 Mexico Heart Blocks Treatment Devices Sales and Growth Rate (2013-2018) 6 Europe Heart Blocks Treatment Devices by Countries 6.1 Europe Heart Blocks Treatment Devices Sales, Revenue and Market Share by Countries 6.1.1 Europe Heart Blocks Treatment Devices Sales and Market Share by Countries (2013-2018) 6.1.2 Europe Heart Blocks Treatment Devices Revenue and Market Share by Countries (2013-2018) 6.2 Germany Heart Blocks Treatment Devices Sales and Growth Rate (2013-2018) 6.3 UK Heart Blocks Treatment Devices Sales and Growth Rate (2013-2018) 6.4 France Heart Blocks Treatment Devices Sales and Growth Rate (2013-2018) 6.5 Russia Heart Blocks Treatment Devices Sales and Growth Rate (2013-2018) 6.6 Italy Heart Blocks Treatment Devices Sales and Growth Rate (2013-2018) 7 Asia-Pacific Heart Blocks Treatment Devices by Countries 7.1 Asia-Pacific Heart Blocks Treatment Devices Sales, Revenue and Market Share by Countries 7.1.1 Asia-Pacific Heart Blocks Treatment Devices Sales and Market Share by Countries (2013-2018) 7.1.2 Asia-Pacific Heart Blocks Treatment Devices Revenue and Market Share by Countries (2013-2018) 7.2 China Heart Blocks Treatment Devices Sales and Growth Rate (2013-2018) 7.3 Japan Heart Blocks Treatment Devices Sales and Growth Rate (2013-2018) 7.4 Korea Heart Blocks Treatment Devices Sales and Growth Rate (2013-2018) 7.5 India Heart Blocks Treatment Devices Sales and Growth Rate (2013-2018) 7.6 Southeast Asia Heart Blocks Treatment Devices Sales and Growth Rate (2013-2018) 8 South America Heart Blocks Treatment Devices by Countries 8.1 South America Heart Blocks Treatment Devices Sales, Revenue and Market Share by Countries 8.1.1 South America Heart Blocks Treatment Devices Sales and Market Share by Countries (2013-2018) 8.1.2 South America Heart Blocks Treatment Devices Revenue and Market Share by Countries (2013-2018) 8.2 Brazil Heart Blocks Treatment Devices Sales and Growth Rate (2013-2018) 8.3 Argentina Heart Blocks Treatment Devices Sales and Growth Rate (2013-2018) 8.4 Colombia Heart Blocks Treatment Devices Sales and Growth Rate (2013-2018) 9 Middle East and Africa Heart Blocks Treatment Devices by Countries 9.1 Middle East and Africa Heart Blocks Treatment Devices Sales, Revenue and Market Share by Countries 9.1.1 Middle East and Africa Heart Blocks Treatment Devices Sales and Market Share by Countries (2013-2018) 9.1.2 Middle East and Africa Heart Blocks Treatment Devices Revenue and Market Share by Countries (2013-2018) 9.2 Saudi Arabia Heart Blocks Treatment Devices Sales and Growth Rate (2013-2018) 9.3 UAE Heart Blocks Treatment Devices Sales and Growth Rate (2013-2018) 9.4 Egypt Heart Blocks Treatment Devices Sales and Growth Rate (2013-2018) 9.5 Nigeria Heart Blocks Treatment Devices Sales and Growth Rate (2013-2018) 9.6 South Africa Heart Blocks Treatment Devices Sales and Growth Rate (2013-2018) 10 Global Heart Blocks Treatment Devices Market Segment by Type 10.1 Global Heart Blocks Treatment Devices Sales, Revenue and Market Share by Type (2013-2018) 10.1.1 Global Heart Blocks Treatment Devices Sales and Market Share by Type (2013-2018) 10.1.2 Global Heart Blocks Treatment Devices Revenue and Market Share by Type (2013-2018) 10.2 Sinoatrial node (SA node) nodal block Sales Growth and Price 10.2.1 Global Sinoatrial node (SA node) nodal block Sales Growth (2013-2018) 10.2.2 Global Sinoatrial node (SA node) nodal block Price (2013-2018) 10.3 Atrioventricular node (AV node) nodal block Sales Growth and Price 10.3.1 Global Atrioventricular node (AV node) nodal block Sales Growth (2013-2018) 10.3.2 Global Atrioventricular node (AV node) nodal block Price (2013-2018) 11 Global Heart Blocks Treatment Devices Market Segment by Application 11.1 Global Heart Blocks Treatment Devices Sales Market Share by Application (2013-2018) 11.2 Hosptial Sales Growth (2013-2018) 11.3 Clinic Sales Growth (2013-2018) 12 Heart Blocks Treatment Devices Market Forecast (2018-2023) 12.1 Global Heart Blocks Treatment Devices Sales, Revenue and Growth Rate (2018-2023) 12.2 Heart Blocks Treatment Devices Market Forecast by Regions (2018-2023) 12.2.1 North America Heart Blocks Treatment Devices Market Forecast (2018-2023) 12.2.2 Europe Heart Blocks Treatment Devices Market Forecast (2018-2023) 12.2.3 Asia-Pacific Heart Blocks Treatment Devices Market Forecast (2018-2023) 12.2.4 South America Heart Blocks Treatment Devices Market Forecast (2018-2023) 12.2.5 Middle East and Africa Heart Blocks Treatment Devices Market Forecast (2018-2023) 12.3 Heart Blocks Treatment Devices Market Forecast by Type (2018-2023) 12.3.1 Global Heart Blocks Treatment Devices Sales Forecast by Type (2018-2023) 12.3.2 Global Heart Blocks Treatment Devices Market Share Forecast by Type (2018-2023) 12.4 Heart Blocks Treatment Devices Market Forecast by Application (2018-2023) 12.4.1 Global Heart Blocks Treatment Devices Sales Forecast by Application (2018-2023) 12.4.2 Global Heart Blocks Treatment Devices Market Share Forecast by Application (2018-2023) 13 Sales Channel, Distributors, Traders and Dealers 13.1 Sales Channel 13.1.1 Direct Marketing 13.1.2 Indirect Marketing 13.1.3 Marketing Channel Future Trend 13.2 Distributors, Traders and Dealers 14 Research Findings and Conclusion 15 Appendix 15.1 Methodology 15.2 Data Source

List of Tables and Figures Figure Heart Blocks Treatment Devices Picture Table Product Specifications of Heart Blocks Treatment Devices Figure Global Sales Market Share of Heart Blocks Treatment Devices by Types in 2017 Table Heart Blocks Treatment Devices Types for Major Manufacturers Figure Sinoatrial node (SA node) nodal block Picture Figure Atrioventricular node (AV node) nodal block Picture Figure Heart Blocks Treatment Devices Sales Market Share by Applications in 2017 Figure Hosptial Picture Figure Clinic Picture Figure United States Heart Blocks Treatment Devices Revenue (Value) and Growth Rate (2013-2023) Figure Canada Heart Blocks Treatment Devices Revenue (Value) and Growth Rate (2013-2023) Figure Mexico Heart Blocks Treatment Devices Revenue (Value) and Growth Rate (2013-2023) Figure Germany Heart Blocks Treatment Devices Revenue (Value) and Growth Rate (2013-2023) Figure France Heart Blocks Treatment Devices Revenue (Value) and Growth Rate (2013-2023) Figure UK Heart Blocks Treatment Devices Revenue (Value) and Growth Rate (2013-2023) Figure Russia Heart Blocks Treatment Devices Revenue (Value) and Growth Rate (2013-2023) Figure Italy Heart Blocks Treatment Devices Revenue (Value) and Growth Rate (2013-2023) Figure China Heart Blocks Treatment Devices Revenue (Value) and Growth Rate (2013-2023) Figure Japan Heart Blocks Treatment Devices Revenue (Value) and Growth Rate (2013-2023) Figure Korea Heart Blocks Treatment Devices Revenue (Value) and Growth Rate (2013-2023) Figure India Heart Blocks Treatment Devices Revenue (Value) and Growth Rate (2013-2023) Figure Southeast Asia Heart Blocks Treatment Devices Revenue (Value) and Growth Rate (2013-2023) Figure Brazil Heart Blocks Treatment Devices Revenue (Value) and Growth Rate (2013-2023) Figure Egypt Heart Blocks Treatment Devices Revenue (Value) and Growth Rate (2013-2023) Figure Saudi Arabia Heart Blocks Treatment Devices Revenue (Value) and Growth Rate (2013-2023) Figure South Africa Heart Blocks Treatment Devices Revenue (Value) and Growth Rate (2013-2023) Figure Nigeria Heart Blocks Treatment Devices Revenue (Value) and Growth Rate (2013-2023) Table Medtronic, Inc. Basic Information, Manufacturing Base and Competitors Table Medtronic, Inc. Heart Blocks Treatment Devices Type and Applications Table Medtronic, Inc. Heart Blocks Treatment Devices Sales, Price, Revenue, Gross Margin and Market Share (2016-2017) Table Boston Scientific Corporation Basic Information, Manufacturing Base and Competitors Table Boston Scientific Corporation Heart Blocks Treatment Devices Type and Applications Table Boston Scientific Corporation Heart Blocks Treatment Devices Sales, Price, Revenue, Gross Margin and Market Share (2016-2017) Table St. Jude Medical, Inc. Basic Information, Manufacturing Base and Competitors Table St. Jude Medical, Inc. Heart Blocks Treatment Devices Type and Applications Table St. Jude Medical, Inc. Heart Blocks Treatment Devices Sales, Price, Revenue, Gross Margin and Market Share (2016-2017) Table BIOTRONIK SE & Co. KG Basic Information, Manufacturing Base and Competitors Table BIOTRONIK SE & Co. KG Heart Blocks Treatment Devices Type and Applications Table BIOTRONIK SE & Co. KG Heart Blocks Treatment Devices Sales, Price, Revenue, Gross Margin and Market Share (2016-2017) Table SORIN S.p.A. Basic Information, Manufacturing Base and Competitors Table SORIN S.p.A. Heart Blocks Treatment Devices Type and Applications Table SORIN S.p.A. Heart Blocks Treatment Devices Sales, Price, Revenue, Gross Margin and Market Share (2016-2017) Table Global Heart Blocks Treatment Devices Sales by Manufacturer (2016-2017) Figure Global Heart Blocks Treatment Devices Sales Market Share by Manufacturer in 2016 Figure Global Heart Blocks Treatment Devices Sales Market Share by Manufacturer in 2017 Table Global Heart Blocks Treatment Devices Revenue by Manufacturer (2016-2017) Figure Global Heart Blocks Treatment Devices Revenue Market Share by Manufacturer in 2016 Figure Global Heart Blocks Treatment Devices Revenue Market Share by Manufacturer in 2017 Figure Top 3 Heart Blocks Treatment Devices Manufacturer (Revenue) Market Share in 2017 Figure Top 6 Heart Blocks Treatment Devices Manufacturer (Revenue) Market Share in 2017 Figure Global Heart Blocks Treatment Devices Sales and Growth Rate (2013-2018) Figure Global Heart Blocks Treatment Devices Revenue and Growth Rate (2013-2018) Table Global Heart Blocks Treatment Devices Sales by Regions (2013-2018) Table Global Heart Blocks Treatment Devices Sales Market Share by Regions (2013-2018) Table Global Heart Blocks Treatment Devices Revenue by Regions (2013-2018) Figure Global Heart Blocks Treatment Devices Revenue Market Share by Regions in 2013 Figure Global Heart Blocks Treatment Devices Revenue Market Share by Regions in 2017 Figure North America Heart Blocks Treatment Devices Sales and Growth Rate (2013-2018) Figure Europe Heart Blocks Treatment Devices Sales and Growth Rate (2013-2018) Figure Asia-Pacific Heart Blocks Treatment Devices Sales and Growth Rate (2013-2018) Figure South America Heart Blocks Treatment Devices Sales and Growth Rate (2013-2018) Figure Middle East and Africa Heart Blocks Treatment Devices Sales and Growth Rate (2013-2018) Figure North America Heart Blocks Treatment Devices Revenue and Growth Rate (2013-2018) Table North America Heart Blocks Treatment Devices Sales by Countries (2013-2018) Table North America Heart Blocks Treatment Devices Sales Market Share by Countries (2013-2018) Figure North America Heart Blocks Treatment Devices Sales Market Share by Countries in 2013 Figure North America Heart Blocks Treatment Devices Sales Market Share by Countries in 2017 Table North America Heart Blocks Treatment Devices Revenue by Countries (2013-2018) Table North America Heart Blocks Treatment Devices Revenue Market Share by Countries (2013-2018) Figure North America Heart Blocks Treatment Devices Revenue Market Share by Countries in 2013 Figure North America Heart Blocks Treatment Devices Revenue Market Share by Countries in 2017 Figure United States Heart Blocks Treatment Devices Sales and Growth Rate (2013-2018) Figure Canada Heart Blocks Treatment Devices Sales and Growth Rate (2013-2018) Figure Mexico Heart Blocks Treatment Devices Sales and Growth Rate (2013-2018) Figure Europe Heart Blocks Treatment Devices Revenue and Growth Rate (2013-2018) Table Europe Heart Blocks Treatment Devices Sales by Countries (2013-2018) Table Europe Heart Blocks Treatment Devices Sales Market Share by Countries (2013-2018) Table Europe Heart Blocks Treatment Devices Revenue by Countries (2013-2018) Figure Europe Heart Blocks Treatment Devices Revenue Market Share by Countries in 2016 Figure Europe Heart Blocks Treatment Devices Revenue Market Share by Countries in 2017 Figure Germany Heart Blocks Treatment Devices Sales and Growth Rate (2013-2018) Figure UK Heart Blocks Treatment Devices Sales and Growth Rate (2013-2018) Figure France Heart Blocks Treatment Devices Sales and Growth Rate (2013-2018) Figure Russia Heart Blocks Treatment Devices Sales and Growth Rate (2013-2018) Figure Italy Heart Blocks Treatment Devices Sales and Growth Rate (2013-2018) Figure Asia-Pacific Heart Blocks Treatment Devices Revenue and Growth Rate (2013-2018) Table Asia-Pacific Heart Blocks Treatment Devices Sales by Countries (2013-2018) Table Asia-Pacific Heart Blocks Treatment Devices Sales Market Share by Countries (2013-2018) Figure Asia-Pacific Heart Blocks Treatment Devices Sales Market Share by Countries 2017 Table Asia-Pacific Heart Blocks Treatment Devices Revenue by Countries (2013-2018) Figure Asia-Pacific Heart Blocks Treatment Devices Revenue Market Share by Countries 2017 Figure China Heart Blocks Treatment Devices Sales and Growth Rate (2013-2018) Figure Japan Heart Blocks Treatment Devices Sales and Growth Rate (2013-2018) Figure Korea Heart Blocks Treatment Devices Sales and Growth Rate (2013-2018) Figure India Heart Blocks Treatment Devices Sales and Growth Rate (2013-2018) Figure Southeast Asia Heart Blocks Treatment Devices Sales and Growth Rate (2013-2018) Figure South America Heart Blocks Treatment Devices Revenue and Growth Rate (2013-2018) Table South America Heart Blocks Treatment Devices Sales by Countries (2013-2018) Table South America Heart Blocks Treatment Devices Sales Market Share by Countries (2013-2018) Figure South America Heart Blocks Treatment Devices Sales Market Share by Countries in 2017 Table South America Heart Blocks Treatment Devices Revenue by Countries (2013-2018) Table South America Heart Blocks Treatment Devices Revenue Market Share by Countries (2013-2018) Figure South America Heart Blocks Treatment Devices Revenue Market Share by Countries in 2017 Figure Brazil Heart Blocks Treatment Devices Sales and Growth Rate (2013-2018) Figure Argentina Heart Blocks Treatment Devices Sales and Growth Rate (2013-2018) Figure Colombia Heart Blocks Treatment Devices Sales and Growth Rate (2013-2018) Figure Middle East and Africa Heart Blocks Treatment Devices Revenue and Growth Rate (2013-2018) Table Middle East and Africa Heart Blocks Treatment Devices Sales by Countries (2013-2018) Table Middle East and Africa Heart Blocks Treatment Devices Sales Market Share by Countries (2013-2018) Figure Middle East and Africa Heart Blocks Treatment Devices Sales Market Share by Countries in 2017 Table Middle East and Africa Heart Blocks Treatment Devices Revenue by Countries (2013-2018) Table Middle East and Africa Heart Blocks Treatment Devices Revenue Market Share by Countries (2013-2018) Figure Middle East and Africa Heart Blocks Treatment Devices Revenue Market Share by Countries in 2013 Figure Middle East and Africa Heart Blocks Treatment Devices Revenue Market Share by Countries in 2017 Figure Saudi Arabia Heart Blocks Treatment Devices Sales and Growth Rate (2013-2018) Figure UAE Heart Blocks Treatment Devices Sales and Growth Rate (2013-2018) Figure Egypt Heart Blocks Treatment Devices Sales and Growth Rate (2013-2018) Figure Nigeria Heart Blocks Treatment Devices Sales and Growth Rate (2013-2018) Figure South Africa Heart Blocks Treatment Devices Sales and Growth Rate (2013-2018) Table Global Heart Blocks Treatment Devices Sales by Type (2013-2018) Table Global Heart Blocks Treatment Devices Sales Share by Type (2013-2018) Table Global Heart Blocks Treatment Devices Revenue by Type (2013-2018) Table Global Heart Blocks Treatment Devices Revenue Share by Type (2013-2018) Figure Global Sinoatrial node (SA node) nodal block Sales Growth (2013-2018) Figure Global Sinoatrial node (SA node) nodal block Price (2013-2018) Figure Global Atrioventricular node (AV node) nodal block Sales Growth (2013-2018) Figure Global Atrioventricular node (AV node) nodal block Price (2013-2018) Table Global Heart Blocks Treatment Devices Sales by Application (2013-2018) Table Global Heart Blocks Treatment Devices Sales Share by Application (2013-2018) Figure Global Clinic Sales Growth (2013-2018) Figure Global Heart Blocks Treatment Devices Sales, Revenue and Growth Rate (2018-2023) Table Global Heart Blocks Treatment Devices Sales Forecast by Regions (2018-2023) Table Global Heart Blocks Treatment Devices Market Share Forecast by Regions (2018-2023) Figure North America Sales Heart Blocks Treatment Devices Market Forecast (2018-2023) Figure Europe Sales Heart Blocks Treatment Devices Market Forecast (2018-2023) Figure Asia-Pacific Sales Heart Blocks Treatment Devices Market Forecast (2018-2023) Figure South America Sales Heart Blocks Treatment Devices Market Forecast (2018-2023) Figure Middle East and Africa Sales Heart Blocks Treatment Devices Market Forecast (2018-2023) Table Global Heart Blocks Treatment Devices Sales Forecast by Type (2018-2023) Table Global Heart Blocks Treatment Devices Market Share Forecast by Type (2018-2023) Table Global Heart Blocks Treatment Devices Sales Forecast by Application (2018-2023) Table Global Heart Blocks Treatment Devices Market Share Forecast by Application (2018-2023) Table Distributors/Traders/ Dealers List

Medtronic, Inc. Boston Scientific Corporation St. Jude Medical, Inc. BIOTRONIK SE & Co. KG SORIN S.p.A.