Table of Contents Table of Contents 2 Introduction 5 Influenza A Virus, H5N1 Subtype Infections - Overview 6 Influenza A Virus, H5N1 Subtype Infections - Therapeutics Development 7 Influenza A Virus, H5N1 Subtype Infections - Therapeutics Assessment 17 Influenza A Virus, H5N1 Subtype Infections - Companies Involved in Therapeutics Development 25 Influenza A Virus, H5N1 Subtype Infections - Drug Profiles 39 Influenza A Virus, H5N1 Subtype Infections - Dormant Projects 127 Influenza A Virus, H5N1 Subtype Infections - Discontinued Products 131 Influenza A Virus, H5N1 Subtype Infections - Product Development Milestones 132 Appendix 142

List of Tables Number of Products under Development for Influenza A Virus, H5N1 Subtype Infections, H1 2018 Number of Products under Development by Companies, H1 2018 Number of Products under Development by Companies, H1 2018 (Contd..1), H1 2018 Number of Products under Development by Companies, H1 2018 (Contd..2), H1 2018 Number of Products under Development by Universities/Institutes, H1 2018 Products under Development by Companies, H1 2018 Products under Development by Companies, H1 2018 (Contd..1), H1 2018 Products under Development by Companies, H1 2018 (Contd..2), H1 2018 Products under Development by Universities/Institutes, H1 2018 Number of Products by Stage and Target, H1 2018 Number of Products by Stage and Mechanism of Action, H1 2018 Number of Products by Stage and Route of Administration, H1 2018 Number of Products by Stage and Molecule Type, H1 2018 Influenza A Virus, H5N1 Subtype Infections - Pipeline by Akshaya Bio Inc, H1 2018 Influenza A Virus, H5N1 Subtype Infections - Pipeline by Altimmune Inc, H1 2018 Influenza A Virus, H5N1 Subtype Infections - Pipeline by Antigen Express Inc, H1 2018 Influenza A Virus, H5N1 Subtype Infections - Pipeline by Aphios Corp, H1 2018 Influenza A Virus, H5N1 Subtype Infections - Pipeline by AusBio Ltd, H1 2018 Influenza A Virus, H5N1 Subtype Infections - Pipeline by BiondVax Pharmaceuticals Ltd, H1 2018 Influenza A Virus, H5N1 Subtype Infections - Pipeline by CEL-SCI Corp, H1 2018 Influenza A Virus, H5N1 Subtype Infections - Pipeline by Cocrystal Pharma Inc, H1 2018 Influenza A Virus, H5N1 Subtype Infections - Pipeline by Curevac AG, H1 2018 Influenza A Virus, H5N1 Subtype Infections - Pipeline by Gemmus Pharma Inc, H1 2018 Influenza A Virus, H5N1 Subtype Infections - Pipeline by GlaxoSmithKline Plc, H1 2018 Influenza A Virus, H5N1 Subtype Infections - Pipeline by Hemispherx Biopharma Inc, H1 2018 Influenza A Virus, H5N1 Subtype Infections - Pipeline by iBio Inc, H1 2018 Influenza A Virus, H5N1 Subtype Infections - Pipeline by Inovio Pharmaceuticals Inc, H1 2018 Influenza A Virus, H5N1 Subtype Infections - Pipeline by Johnson & Johnson, H1 2018 Influenza A Virus, H5N1 Subtype Infections - Pipeline by Karyopharm Therapeutics Inc, H1 2018 Influenza A Virus, H5N1 Subtype Infections - Pipeline by Kineta Inc, H1 2018 Influenza A Virus, H5N1 Subtype Infections - Pipeline by Lakewood-Amedex Inc, H1 2018 Influenza A Virus, H5N1 Subtype Infections - Pipeline by Medicago Inc, H1 2018 Influenza A Virus, H5N1 Subtype Infections - Pipeline by Medigen Vaccine Biologics Corp, H1 2018 Influenza A Virus, H5N1 Subtype Infections - Pipeline by Microbiotix Inc, H1 2018 Influenza A Virus, H5N1 Subtype Infections - Pipeline by NanoBio Corp, H1 2018 Influenza A Virus, H5N1 Subtype Infections - Pipeline by NanoViricides Inc, H1 2018 Influenza A Virus, H5N1 Subtype Infections - Pipeline by Ology Bioservices Inc, H1 2018 Influenza A Virus, H5N1 Subtype Infections - Pipeline by OPKO Health Inc, H1 2018 Influenza A Virus, H5N1 Subtype Infections - Pipeline by PaxVax Inc, H1 2018 Influenza A Virus, H5N1 Subtype Infections - Pipeline by PeptiDream Inc, H1 2018 Influenza A Virus, H5N1 Subtype Infections - Pipeline by Shionogi & Co Ltd, H1 2018 Influenza A Virus, H5N1 Subtype Infections - Pipeline by TechnoVax Inc, H1 2018 Influenza A Virus, H5N1 Subtype Infections - Pipeline by Vaxart Inc, H1 2018 Influenza A Virus, H5N1 Subtype Infections - Pipeline by Vaxine Pty Ltd, H1 2018 Influenza A Virus, H5N1 Subtype Infections - Pipeline by VirionHealth Ltd, H1 2018 Influenza A Virus, H5N1 Subtype Infections - Dormant Projects, H1 2018 Influenza A Virus, H5N1 Subtype Infections - Dormant Projects, H1 2018 (Contd..1), H1 2018 Influenza A Virus, H5N1 Subtype Infections - Dormant Projects, H1 2018 (Contd..2), H1 2018 Influenza A Virus, H5N1 Subtype Infections - Dormant Projects, H1 2018 (Contd..3), H1 2018 Influenza A Virus, H5N1 Subtype Infections - Discontinued Products, H1 2018List of Figures Number of Products under Development for Influenza A Virus, H5N1 Subtype Infections, H1 2018 Number of Products under Development by Companies, H1 2018 Number of Products under Development by Universities/Institutes, H1 2018 Number of Products by Top 10 Targets, H1 2018 Number of Products by Stage and Top 10 Targets, H1 2018 Number of Products by Top 10 Mechanism of Actions, H1 2018 Number of Products by Stage and Top 10 Mechanism of Actions, H1 2018 Number of Products by Routes of Administration, H1 2018 Number of Products by Stage and Routes of Administration, H1 2018 Number of Products by Top 10 Molecule Types, H1 2018 Number of Products by Stage and Top 10 Molecule Types, H1 2018